Behind The Technology of Autonomix

For the first time ever, the Autonomix technology has the potential to navigate the nervous system to provide real-time precision-guided therapy. Clinical trials start early next year.


More Sensitive


“First-in-class” Electrophysiology Technology


Years of Combined Team Experience with a Proven Track Record of Developments, Approvals and Exits


Distinct Wholly Owned Patent Families

Fact #1

Understanding the Nervous System

The nervous system is how your body communicates information to the brain, and vice versa. It transmits pain signals, controls voluntary and involuntary actions of the body, controls blood pressure, and regulates digestion and more.

Fact #2

Navigating the Body’s Superhighway

The peripheral nervous system travels through the body alongside the vascular system—which means your veins and arteries can act as a “superhighway” that allows doctors to access nearly any nerve within the body through the use of commonplace catheters.

Fact #3

Going Where No Tech Has Gone Before

Until now, no clinically available technology has been sensitive enough to read the electric signals sent out by your peripheral nervous system. Autonomix is designing technology that has the ability to detect these weak malfunctioning signals, paving the way for treatment not yet available in the market today.

How Autonomix Uses This Science

Scientists have long known the nervous system is how the body interprets pain, but until now there’s been no way to navigate it to provide precise treatment. The Autonomix catheter-based technology acts like a precision guided smart bomb, allowing doctors to find and destroy the specific target nerves, through ablation or burning, that are misfiring to alleviate pain.

About Our Technology

With our catheter-based sensing technology, we’re developing the ability to do two things at once: sense neural signals that indicate pain or disease and destroy those nerves at the source.

We believe this is a better alternative to the current approaches commonly used today, where doctors treat suspected areas in an attempt to hit the right nerves. This approach is often inaccurate and can miss the target and even cause collateral damage to surrounding nerves.

The Autonomix technology uses our proprietary microchip and unique antenna sensing array to deliver precise treatments through a simple and safe transvascular procedure.


Custom Antenna Array

Our state-of-the-art custom antennae array detects, maps, displays and modulates the problem accurately and safely.

Guidewire & Catheter Bodies

Small enough to reach any organ.

Proprietary Chipset

Equipped with embedded microelectronics, our patented chipset enables robust nerve signal processing at the source.

How It Works

Step 1

Proprietary Microchip

The Autonomix catheter is equipped with a microchip that converts analog signals from the body to a digital signal that can be sent directly to a computer screen. This means the faint neural signals don’t have to travel through several feet of wires—they’re read right on the spot.

Step 2

Sensing Antenna Array

Our sensing antenna is sensitive enough to detect signals as low as 0.5 microvolts (as opposed to the 10-15 microvolt minimum detectable by current technology). The unique basket design can locate neural signals in a 3D space for the most precise treatment possible.

Step 3

Simple, Minimally Invasive Procedure

Our technology is designed to do more than just locate neural signals. In the future, with just a single quick procedure, we will be able to locate, ablate and confirm successful ablation of specific nerves.

Who We Help

Ultimately, we believe the Autonomix technology can be used to treat a large number of diseases relating to the dysregulation of the nervous system. We are initially focusing our efforts by helping pancreatic cancer patients and people with pancreatitis who are suffering from pain that is not relieved by currently available methods.

These patients suffer excruciating pain, and current pain relief options are limited to drugs, such as opioids, that lose effectiveness over time, or cause severe side effects.

Our goal is to provide pain relief and a better quality of life for these patients by giving them safer, more effective relief. Once we prove the effectiveness of our technology, we can expand our reach to provide even more treatment options and help even more patients.

Frequently Asked Questions

We are developing what we believe to be a better alternative to the current approaches commonly used today, where doctors treat suspected areas in an attempt to hit the right nerves. This approach is often inaccurate and can miss the target and even cause collateral damage to surrounding nerves.

We believe our technology can potentially treat a large number of diseases related to the dysregulation of the nervous system, including chronic pain, cardiovascular disease and pulmonary disease. Our initial focus is on helping pancreatic cancer patients and people with pancreatitis suffering from severe pain not adequately managed with existing methods. We believe this approach provides us the best opportunity to demonstrate “proof of concept” while being the quickest to market.

Autonomix’s technology holds the potential to usher in a new era of personalized medicine by allowing doctors to tailor treatments to individual neural profiles. This precision can lead to more effective interventions, fewer side effects and improved patient experiences across a spectrum of diseases.

The transvascular approach is groundbreaking because it enables doctors to access nearly any nerve within the body through familiar catheters. This approach opens new avenues for minimally invasive diagnosis and targeted treatment of conditions involving the peripheral nervous system, offering patients safer and more effective solutions.

Autonomix achieves high sensitivity by using the patented microchip small enough to place immediately adjacent to the antenna detecting the signals, which greatly reduces the distance the signals must travel.

This approach provides a safer and more effective alternative by targeting the specific nerves responsible for pain or disease. This minimizes the reliance on painkillers and opioids, which often come with side effects and diminishing effectiveness over time. The goal is to improve patient outcomes and quality of life by offering precise and lasting relief.

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